Columbus Crew vs Inter Miami CF Best odds and tips

Columbus Crew and Inter Miami CF can make an early statement in the MLS 2025 title race when they face off at Lower.com Field on Saturday in what is quickly becoming one of the most intriguing rivalries in the division. Crew are the slight favourites at 2.25 with Miami available at 3.30 to win on the road, which seems a fair reflection of the two clubs’ home and away form respectively. Wilfried Nancy’s men have made a strong start to the campaign, sitting second in the MLS 2025 table with 18 points from eight games. The Crew boss has installed a possession-based system that suits the players he has at his disposal and they have played some excellent football at times this season. A 3-4-2-1 formation allows them to dominate territory with their short-passing style, rotate players fluidly and build up in a structured manner. Nancy, who took over in December 2022, has created a team that plays a system first and players second, which has served them well so far. Inter Miami CF are fifth in the table with 15 points from seven games, so they are also close to the summit of the MLS. Javier Mascherano has settled in well since taking over as head coach in November 2024 and he has made the most of his star-studded attacking options by deploying them in a flexible 4-3-3 or 4-2-3-1 formation.

The visitors prefer to play direct football and get Messi and Suarez on the ball as quickly as possible so they can use their individual brilliance to unlock the opposition defence. Luis Suarez has been the provider this season, creating 5 assists in 7 MLS matches, while Messi is the main man up top with three in five appearances. The Argentine ace has scored four goals in his last five Miami appearances, while Diego Rossi leads the line for Columbus with five in eight MLS games. The Crew’s striker has scored four in his last five, so both men can make a difference in this early-season showdown. Columbus have won three of their last five MLS games, while Miami have won two of their last three visits to Ohio, so the hosts are taken to edge this encounter with both teams to score also a worthwhile addition to the bet. Columbus have scored six goals in four home games (average 1.5 per game) and Miami have hit two per game on the road, so we could see a few goals in this clash of collective structure versus star power.

Columbus Crew have won two and drawn two of their four MLS 2025 home games, while Inter Miami CF have won two and drawn one of their three away games, so the hosts are favoured here. Columbus have won three of their last five MLS games and Miami have drawn one and lost one of their last two away, so home advantage and superior momentum should see Crew through. The visitors have won three of the last five head-to-head meetings between these clubs, with Columbus taking one and one draw in all competitions. The Crew edged Miami 3-2 at home in the 2024 CONCACAF Leagues Cup and have the momentum to repeat the trick here.