San Diego FC vs Colorado Rapids Best odds and tips

San Diego FC are the bookmakers’ favourites to win this MLS 2025 fixture at 1.68, which is about right given that Colorado Rapids are clear underdogs at 4.22. The home side are in the top half of the table in eighth place with 20 points from 12 games while Colorado are languishing in 20th with 16. These two sides have met just once before in MLS 2025, four weeks ago, with Colorado winning 3-2 at home. San Diego have since beaten St. Louis City away and thrashed FC Dallas 5-0 at home to show that they are on the up. Mikey Varas took charge of San Diego in September 2024 and has quickly got his team playing with a clear identity, which is to ride or die in a possession-based style. They usually control the midfield in their 4-3-3 system, but Colorado Rapids are yet to find their tactical identity after Chris Armas took over in November 2023.

Anders Dreyer is the star of the San Diego show with five goals and three assists in 12 league appearances, but Hirving Lozano is the player in form with three goals in the last five. Djordje Mihailovic leads the line for Colorado Rapids with five goals in 12 MLS games, but he has three in his last five appearances. Conference standings add extra spice to this game with both sides battling for critical Western Conference points. Colorado Rapids have a balanced away record with two wins, two draws and two defeats in six away games this season, but they have only scored six goals in those six trips. San Diego have won one and lost one of their last two home MLS 2025 matches, but their recent surge in goals makes us think that the over 2.5 goals market could be the smart bet here. We will take the home side to win this one, however, because of their ability to control the midfield and pass the ball, which Colorado Rapids lack.